Fractional CO2 Recovery, Day by Day: What the Two Weeks Actually Look Like

The most powerful resurfacing tool we have, and the one most often used on the wrong patient. Here is what the treatment does to skin, who it suits, and an honest day-by-day account of the recovery nobody describes in advance.

Last reviewed 1 September 2026Reviewed quarterly
Fractional CO2RecoveryRF microneedlingIPLChemical peels
Treatment depth by deviceA depth chart of facial skin from the surface down to five millimeters, marked with the epidermis, papillary dermis, reticular dermis, subcutaneous fat and the SMAS. Six treatments are plotted as vertical bars showing the depth each reaches: IPL from about 0.05 to 1 millimeter; a medium-depth chemical peel from the surface to about 0.45 millimeters; fractional CO2 from the surface to about 1.6 millimeters; non-ablative fractional laser from about 0.25 to 1.4 millimeters; radiofrequency microneedling from about 0.5 to 3.5 millimeters; and microfocused ultrasound at three discrete focal depths of 1.5, 3 and 4.5 millimeters with untreated tissue in between.EpidermisPapillary dermisReticular dermisSubcutaneous fatSMAS0 mm1 mm2 mm3 mm4 mm5 mmDepthIPLMediumpeelFractionalCO2Non-ablativefractionalRFmicroneedlingMicrofocusedultrasoundTypical facial settings. Depth is operator-adjustable on every device here except the peel.
Which layer each device actually reaches in facial skin. Depths are typical facial settings and are operator-adjustable — the point is the ordering, not the millimeter. Focused ultrasound is drawn as separate bands because it deposits energy at discrete focal points and leaves the tissue between them alone.Illustration: facelove.info
Jump to

A fractional CO2 laser drills thousands of microscopic columns of controlled injury through the skin, leaving untreated tissue between them. As those columns heal, new collagen is laid down and the surface contracts slightly. That is the resurfacing effect, and nothing else available does it as thoroughly.

It is also the treatment I turn down most often.

Where it works, and what else reaches that depth

Almost every "which laser should I have" question resolves once you can see that these devices are not competing at the same depth.

A peel and an IPL never leave the upper dermis. IPL is a pigment and vessel tool with essentially no effect on texture. A non-ablative fractional laser heats the dermis without removing tissue, which means less downtime and less change per session. Radiofrequency microneedling reaches deeper than any of them because the needle depth is a setting, and focused ultrasound skips everything above its focal points entirely.

Fractional CO2 occupies the range where old sun damage, etched fine lines, texture and mild laxity actually live. That is why the results are what they are, and it is also why the recovery is what it is. The two are the same fact.

Who it suits

Three things decide candidacy.

Skin type. The risk that matters is post-inflammatory hyperpigmentation. In darker skin types, a treatment that produces controlled injury across the whole face carries a real chance of leaving pigment behind that takes months to resolve. That does not make CO2 off the table, but it changes the settings, the pre-treatment, and honestly the risk-benefit conversation.

What is actually wrong. CO2 addresses the surface and the upper dermis. It does very little for descent and nothing for volume. Someone whose complaint is a jowl and a hollow midface will not get what they want from a laser, and will have spent two weeks recovering to find that out.

Whether you can take the downtime seriously. This is the one people underestimate, so the rest of this page is about it.

Before the treatment

If you are prone to cold sores, you take an antiviral before we start. A resurfaced face is an ideal surface for a herpes outbreak, and an outbreak across healing skin is how you get a scar.

Anything medicated comes out of your skincare at least a week beforehand, and after the treatment nothing goes on your face except what we tell you to put there.

Day by day

This is the honest version, and it describes one aggressive pass — the treatment I actually do. It is deliberately not a series of light sessions. Light passes do roughly what a superficial peel does, which is a real thing but almost never the thing people come to me for. The aggressive setting is what reaches deep enough to change a deep line, so the recovery below is the price of the result being visible.

Day 0. The numbing wears off and it burns. Many people also itch. The skin is bright red immediately.

Days 1 to 3. This is the worst of it and I would rather you hear it now than discover it. The skin oozes, then crusts, then scabs. It is bright red and swollen. You look exaggerated and frankly alarming, like your face has been burned — because in a controlled sense it has.

Two things run continuously through this window. Aquaphor, to keep everything moist so the crusts and scabs do not build. And vinegar soaks, which keep the tissue clean, settle the inflammatory response, and lift the crusting off as the skin heals underneath. You are also on a steroid through this stretch, particularly if we did a deep plane face and neck lift at the same sitting.

Days 4 to 5. The oozing is easing. What is left is an intense red and a lot of swelling. Do not plan anything. Do not go outside into sun. If you would mind someone looking at you strangely, do not plan to be looked at.

Day 7. The oozing and crusting are essentially finished. You are left with skin that is a bright, intense red, and that color is what takes weeks to go.

Day 10. Foundation covers enough to go out if you need to.

Day 14. Restaurant ready, with a lot of foundation.

Week 6. We photograph you. There is often still some pink, sometimes splotchy. That is expected, and it is not a complication.

Month 3. Most of it is gone.

What people underestimate

The healing time, every time. Most patients are fine with the idea of a week or two. What catches them is day ten to day fourteen, when the crusting is long gone and the skin is still unmistakably pink, and it stays that way for weeks more. That is the moment people get frustrated.

If the redness is intense and persisting, a short course of a steroid cream can help, and it is worth reviewing what you are putting on your face at home, because a product you have gone back to too early is a common cause.

Who I will not treat, and how I decide

Post-inflammatory hyperpigmentation is the complication that matters here, and the risk runs with skin type. In darker skin types I generally do not recommend fractional CO2 at all.

For someone sitting on the border between Fitzpatrick II and III, I test. We laser a small inconspicuous area — behind the ear, or on the neck or chest — and watch it over the following weeks. If that patch pigments, we do not laser the face. It costs a few weeks to find out, and it is a great deal cheaper than discovering it across someone's cheeks.

Where the treatment goes wrong

Four patterns account for most of the poor outcomes I see.

Treating the wrong problem, discussed above. Treating skin that has not been prepared, particularly where pigmentation is a risk. Settings chosen for a brochure result on skin that could not tolerate them. And patients who did not grasp what days one to six involve, stopped the aftercare, and had a healing problem as a result.

None of those are failures of the technology.

The question worth asking your provider

If you have been told you are a candidate, the useful follow-up is why. A provider who can name which of your specific findings this treatment addresses, and which of them it will not touch, is thinking about your skin. A provider whose answer is that it improves everything has told you something about their practice.

The verdicts on this

All verdicts →
ModestEvidence grade BEnergy & Resurfacing

Radiofrequency Microneedling

Real deep-dermal remodeling in mild to moderate laxity, and consistently oversold as a facelift alternative.

Last reviewed 1 September 2026

ModestEvidence grade BEnergy & Resurfacing

Chemical Peels

Depth is everything. Superficial peels do a little; medium-depth peels do a lot and carry matching downtime.

Last reviewed 1 September 2026

ModestEvidence grade BEnergy & Resurfacing

Microneedling

Consistent, modest improvement in texture and acne scarring across several sessions.

Last reviewed 1 September 2026

Recent coverage

All news →
NewsEnergy & Resurfacing2 September 2026

Do Retinoids Protect Darker Skin After Ablative Laser?

Dermatologic Surgery examined whether patients using a retinoid around the time of ablative laser resurfacing developed less post-inflammatory hyperpigmentation, in the skin types where that risk is highest. Pigment left behind after resurfacing is the complication that decides candidacy in darker skin, and it is why a treatment that suits one patient is a poor idea for another with the same finding. Anything that shifts that risk changes the conversation about who is a candidate, not the settings on the machine.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], “Post-inflammatory Hyperpigmentation After Ablative Laser Resurfacing in Darker Skin: Are Concurrent Retinoids Protective?” — read the original

NewsEnergy & Resurfacing29 August 2026

A Rare Stroke After Laser Resurfacing, and the Mechanism

Lasers in Surgery and Medicine reports a sixty-two-year-old woman who suffered an embolic stroke after full-field ablative Erbium:YAG resurfacing. The proposed mechanism is specific and worth understanding: significant pain during the procedure prompted a Valsalva maneuver, and a previously unknown patent foramen ovale allowed a clot to cross from the venous side to the arterial one. This is a single case report of a first-described event, so it says nothing about the general risk of resurfacing. What it does argue for is adequate anesthesia during ablative treatment, because pain that makes someone bear down is a mechanism and not just discomfort.

Lasers in surgery and medicine, “Stroke Following Facial Laser Resurfacing Procedure-A Case Report.” — read the original

Related guides

All guides →
GuideVolume & Fat Transfer

GLP-1 Weight Loss and the Face: What Empties, and What Puts It Back

The medication is not damaging your face. Fast weight loss is, and it does it through discrete fat compartments that empty at different rates. That mechanism decides which treatments can realistically restore it.

Last reviewed 1 September 2026

Newsletter

The one email a week that isn't selling you something.

What changed in facial rejuvenation this week, one guide we updated, and why it matters. Written by Jay Keni, MD.

A weekly email, once we launch it. We don’t sell or share addresses, and we never add patients from practice records — privacy.

Found something out of date, or something we got wrong? How we handle corrections.