Verdicts
Thin evidenceEvidence grade CSkin & Prevention
At-Home LED Masks
The same mechanism as clinic red light, usually at a dose nobody will tell you.
WorksEvidence grade ASkin & Prevention
Daily Sunscreen
Randomized evidence that daily use measurably slows visible aging over years.
Doesn'tEvidence grade DSkin & Prevention
Gua Sha and Facial Massage
A short-lived reduction in fluid, and no evidence for anything structural.
ModestEvidence grade CSkin & Prevention
Injectable Skin Boosters
A real, measurable improvement in skin hydration and fine texture that fades on a predictable schedule.
Thin evidenceEvidence grade DSkin & Prevention
PRP and PRF for Skin
Most of the studies behind it are uncontrolled, and the reviews that pooled them rate their own confidence as low.
ModestEvidence grade BSkin & Prevention
Red Light Therapy
Real but small, and only with consistent use at an adequate dose.
Thin evidenceEvidence grade DSkin & Prevention
Topical and Injected Exosomes
Genuinely interesting biology, almost no controlled human facial data, and a regulatory position most clinics do not mention.
Thin evidenceEvidence grade DSkin & Prevention
Topical Growth Factor Serums
Large molecules, an intact barrier, and small manufacturer-run studies. The mechanism has a delivery problem.
WorksEvidence grade ASkin & Prevention
Topical Retinoids
The strongest-evidenced topical in dermatology, and the one most people give up on too early.
ModestEvidence grade CSkin & Prevention
Topical Vitamin C
A real but small effect on pigmentation, resting on seven small trials and a formulation that has to stay stable.